Hubungan Status Tekanan Darah Dengan Ketahanan Pasien Covid-19 Tahun 2021 – 2022 Di Rsud Dr. H. Abdul Moeloek Bandar Lampung
Abstract
Penyakit virus Corona 2019 (COVID-19) adalah penyakit menular yang disebabkan oleh sindrom pernapasan akut parah virus corona 2. Faktor resiko COVID-19 paling utama adalah Riwayat kontak dengan pasien terinfeksi COVID-19. Adanya penyakit bawaan seperti hipertensi, diabetes melitus, penyakit kardiovaskular dapat memperberat kondisi pasien COVID-19. Hipertensi ditandai dengan tekanan darah yang terus – menerus tinggi di arteri sistemik. hipertensi dapat menjadi patogenensis terjadinya infeksi COVID-19 dimana virus akan mengikat ACE2 yang ada di paru – paru kemudian penetrasi ke dalam sel sehinggan meningkatkan risiko infeksi berat melalui komolikasi yang terjadi, seperti ARDS, pneumonia, kegagalan multi – organ hingga berujung kematian. Analitik observasional dengan menggunakan pendekatan metode cross sectional menggunakan teknik total sampling. Pengambilan data digunakan ialah sampel yang sesuai kriteria inklusi dan ekslusi sepanjang 2021- 2022. Penelitian ini dilakukan di RSUD Dr. H. Abdul Moeloek. Data statistik uji chi-square menggunakan SPSS 26. Diketahui distribusi status tekanan darah pada pasien COVID- 19 di RSUD Dr. H. Abdul Moeloek Bandar Lampung terbanyak ialah pada status hipertensi derajat 1 sebanyak 32 pasien (56,1%) dan diikuti oleh hipertensi derajat 2 sebanyak 14 pasien (24,6%). Lalu pada status hipertensi derajat 3 sebanyak 4 pasien (7%) dan status hipertensi normal tinggi didapatkan dengan jumlah 7 pasien (12,3%). Diketahui distribusi ketahanan hidup pasien COVID-19 di RSUD Dr. H. Abdul Moeleok Bandar Lampung terbanyak ialah pada pasien hidup sebanyak 47 pasien (82,5%) dan pasien yang meninggal didapatkan 10 pasien (17,2%). Dan diketahui hasil analisis chi-square mendapatkan nilai p-value 0,000 (< 0,05) yang artinya ada hubungan antara tekanan darah dengan ketahanan hidup pasien COVID- 19 di RSUD Dr. H. Abdul Moeloek Bandar Lampung. Terdapat hubungan antara tekanan darah dengan ketahanan hidup pasien COVID-19 di RSUD Dr. H. Abdul Moeloek Bandar Lampung.
References
Adhikari SP, Meng S, Wu YJ, Mao YP, Ye RX, Wang QZ, et al. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. Infect Dis Poverty. 2020 Mar 17;9(1).
Alek, Syahrizal. HUBUNGAN HIPERTENSI TERHADAP TINGKAT KEPARAHAN PASIEN COVID-19 DI RSDC WISMA ATLET KEMAYORAN. 2023;8(1):43–9.
Anwar, A., K, H., As, A., I, S., W, Z., N, S., R, M., S, U., J, F., & G, A. (2018). Prevalence of Clinical Signs and Symptoms of Hypertension: A Gender and Age Based Comparison. Palliative Medicine & Care: Open Access, 5(2), 1–8. https://doi.org/10.15226/2374-8362/5/2/00155
Bonanad C, García-Blas S, Tarazona-Santabalbina F, Sanchis J, Bertomeu- González V, Fácila L, et al. The effect of age on mortality in patients with COVID-19: a meta-analysis with 611,583 subjects. J Am Med Dir Assoc. 2020 Jul 1;21(7):915–8.
Cascella, M., Rajnik, M., Aleem, A., Dulebohn, S. C., & Napoli, R. D. (2022). Features, Evaluation, and Treatment of Coronavirus (COVID-19). In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK554776/
Chen X, Hu MT W, Yang M, Ling J, Zhang Y, Deng L, et al. Risk factors for the delayed viral clearance in COVID‐19 patients. The Journal of Clinical Hypertension. 2021 Aug 1;23(8):1483.
Chen X, Zhu B, Hong W, Zeng J, He X, Chen J, et al. Associations of clinical characteristics and treatment regimens with the duration of viral RNA shedding in patients with COVID-19. Int J Infect Dis. 2020 Jun 30;98:252–60.
Clark, C. E., Martin, U., & J, sinead T. (2021). COVID-19 and hypertension : risks and management . A scienti fi c statement on behalf of the British and Irish Hypertension Society. Journal of Human Hypertension, 35, 304–307. https://doi.org/10.1038/s41371-020-00451-x
Efriza, E. (2021). COVID-19. Baiturrahmah Medical Journal, 1(1), 60–68.
Escobedo-de, J., Rasc, A., Gonz, E., Fern, E., Borja-bustamante, P., & Santill, A. (2020). Hypertension, Diabetes and Obesity, Major Risk Factors for Death in Patients with COVID-19 in Mexico. Archives of Medical Research, 52(January), 443–449.
Guan W, Liang W, Zhao Y, et al. Comorbidity and its impact on 1590 patients with COVID-19 in China/ : a. 2020;(March 2020).
Hartenian, E., Nandakumar, D., Lari, A., Ly, M., Tucker, J. M., & Glaunsinger, B. A. (2020). The molecular virology of coronaviruses. Journal of Biological Chemistry, 295(37), 12910–12934. https://doi.org/10.1074/jbc.REV120.013930
Huang S, Wang J, Liu F, Liu J, Cao G, Yang C, et al. COVID-19 Patients With Hypertension Have More Severe Disease: A Multicenter Retrospective Observational Study. Hypertension Research. 2020;43(8):824-831.
Huang X, Wei F, Hu L, Wen L, Chen K. Epidemiology and clinical characteristics of COVID-19. Arch Iran Med. 2020;23(4):268–71.
Imam, Z., Odish, F., Gill, I., O’Connor, D., Armstrong, J., Vanood, A., Ibironke, O., Hanna, A., Ranski, A., & Halalau, A. (2020). Older age and comorbidity are independent mortality predictors in a large cohort of 1305 COVID-19 patients in Michigan, United States. Journal of Internal Medicine, 288(4), 469–476. https://doi.org/10.1111/joim.1311
Kemenkes RI. Hipertensi Komorbid Tertinggi COVID-19 melalui siaran Pers Nomor: 109/HUMAS PMK/V/2021. In: RI K, editor. 2021.
Puchalska-Sarna, A., Baran, R., Kustra, M., Pop, T., Herbert, J., & Baran, J. (2022). The Level and Factors Differentiating the Physical Fitness of Adolescents Passively and Actively Resting in South-Eastern Poland—A Pilot Study. Children, 9(9), 1341. https://doi.org/10.3390/children9091341
Rezi, N. S. (2022). Hubungan Status Hipertensi Dengan Ketahanan Hidup Pasien COVID-19 di Kota Padang Tahun 2020-2021 [Diploma, Universitas Andalas]. http://scholar.unand.ac.id/103820/
Rodilla, E., López-carmona,M. D., Cortes, X., Cobos-palacios, L., Canales, S., Sáez, M. C., Escudero, S. C., Rubio-rivas, M., Manglano, J. D., Castro, S. J. F., Piqueras, N. V., Sanchis, E. M., Maria, P., Fontan, P., Oskar, J., Gamboa, M., García, A. G., Romero, V. M., Chamorro, L.T., ... Network, S.-. (2021). Impact of Arterial Stiffness on All-Cause Mortality in Patients Hospitalized With COVID-19 in Spain. March, 856–867. https://doi.org/10.1161/HYPERTENSIONAHA.120.16563
Samrah SM, Al-Mistarehi AH, Kewan T, Al-Khatib SM, Ibnian AM, Samrah RS, et al. Viral clearance course of COVID-19 outbreaks. J Multidiscip Healthc. 2021;14:555.
Sharma, A., Ahmad Farouk, I., & Lal, S. K. (2021). COVID-19: A Review on the Novel Coronavirus Disease Evolution, Transmission, Detection, Control and Prevention. Viruses, 13(2), 202. https://doi.org/10.3390/v13020202
Shereen, M. A., Khan, S., Kazmi, A., Bashir, N., & Siddique, R. (2020). COVID-19 infection: Emergence, transmission, and characteristics of human coronaviruses. Journal of Advanced Research, 24, 91–98. https://doi.org/10.1016/j.jare.2020.03.005
Wang S, Zhang Q, Wang P, Ye H, Jing X, Zhang Z, et al. Clinical features of hypertensive patients with COVID-19 compared with a normotensive group: single-center experience in China. Open Medicine. 2021 Jan 1;16(1):367.
Xu XW, Wu XX, Jiang XG, Xu KJ, Ying LJ, Ma CL, et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov- 2) outside of Wuhan, China: retrospective case series. BMJ. 2020 Feb 19;368:m606–m606.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020 Mar 28;395(10229):1054–62.
